hormone replacement therapy

noun

: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy
The usual treatment for hypothyroidism is hormone replacement therapy.—Kate Murphy
especially : the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis
—abbreviation HRT

Examples of hormone replacement therapy in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The doctor's group, known as ACOG, recommends hormone replacement therapy alongside certain antidepressants, nonhormonal medicines, and other treatments to address symptoms like hot flashes, insomnia and mood swings. — Shannon Firth, NPR, 16 Oct. 2026 That includes advocating for treatments like hormone replacement therapy and even taking the time to masturbate. — Helen Carefoot, Flow Space, 16 Oct. 2026 The American College of Obstetricians and Gynecologists has released new guidance for the treatment of common menopause and perimenopause symptoms, including recommending hormone replacement therapy for many women with hot flashes and night sweats. — Kerry Breen, CBS News, 16 Oct. 2026 The industry as a whole has grown rapidly over the past decade and is built on the demand for drugs targeting common conditions — and that can be accessed discreetly — such as hair loss treatments and hormone replacement therapies. — Anna Cooban, CNN Money, 15 Oct. 2026 See All Example Sentences for hormone replacement therapy

Word History

First Known Use

1945, in the meaning defined above

Time Traveler
The first known use of hormone replacement therapy was in 1945

Rhymes for hormone replacement therapy

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Browse Nearby Words

hormonelike
hormone replacement therapy
hormone therapy
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Cite this Entry

“Hormone replacement therapy.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hormone%20replacement%20therapy. Accessed 20 Oct. 2026.

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Medical Definition

hormone replacement therapy

noun
: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy
The usual treatment for hypothyroidism is hormone replacement therapy.—Kate Murphy
especially : the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis
—abbreviation HRT

More from Merriam-Webster on hormone replacement therapy

Britannica.com: Encyclopedia article about hormone replacement therapy

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